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Non-propellor tip missense mutations have a similar rate of LOH to truncating mutations. Second hits were assigned as in Table 1. Four samples with one non-propellor tip missense mutation and one truncating mutation were assigned as half-data points to each of the two ‘second hit’ categories
| No second hit | Second hit | Total | |
|---|---|---|---|
| Non-propellor tip missense mutation | 17 | 7 | 24 |
| Protein-truncating mutation | 16 | 9 | 25 |
| Total | 33 | 16 | 49 |
