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. Author manuscript; available in PMC: 2015 Oct 6.

Published in final edited form as: Am J Gastroenterol. 2014 Mar 25;109(5):668–675. doi: 10.1038/ajg.2014.47

Table 4.

Association between population density and increasing levels of esophageal eosinophilia

	≥ 15 eos/hpf (n=14,381)^c		≥ 50 eos/hpf (n=3,783)^c		≥ 100 eos/hpf (n=823)^c
Population density^a	OR (95% CI)	aOR^b (95% CI)	OR (95% CI)	aOR^b (95% CI)	OR (95% CI)	aOR^b (95% CI)
1-251	1.28 (1.21, 1.36)	1.27 (1.18, 1.36)	1.38 (1.24, 1.54)	1.45 (1.27, 1.65)	1.36 (1.08, 1.72)	1.51 (1.14, 1.99)
252-820	1.27 (1.20, 1.34)	1.22 (1.15, 1.30)	1.36 (1.22, 1.51)	1.41 (1.25, 1.58)	1.39 (1.11, 1.75)	1.57 (1.22, 2.03)
821-1,937	1.20 (1.13, 1.27)	1.15 (1.08, 1.22)	1.34 (1.20, 1.48)	1.33 (1.19, 1.49)	1.52 (1.23, 1.89)	1.60 (1.26, 2.02)
1,938-3,744	1.20 (1.13, 1.27)	1.15 (1.08, 1.22)	1.28 (1.15, 1.42)	1.23 (1.10, 1.38)	1.41 (1.12, 1.76)	1.39 (1.10, 1.75)
3,745-144,333	Referent	Referent	Referent	Referent	Referent	Referent
p for trend	<0.001	<0.001	<0.001	<0.001	0.016	0.003

^a

Persons per square mile

^b

Adjusted for age, sex, distance patient traveled to endoscopy site, and the proportion in the population in each zip code that reported white race

^c

Number of patients meeting case group definition