Table 2.
Raw and corrected mean GABA+ levels in institutional units obtained from GABA-edited spectra using LCModel with two basis sets (abbreviated as K basis set and G basis set), and corresponding intra-individual and inter-individual coefficients of variation (CVs).
| Left Cerebellar Dentate | Right Cerebellar Dentate | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| K basis set | G basis set | K basis set | G basis set | |||||||||
| Levels | Intra- individual CVs (%) |
Inter- individual CVs (%) |
Levels | Intra- individual CVs (%) |
Inter-individual CVs (%) |
Levels | Intra- individual CVs (%) |
Inter- individual CVs (%) |
Levels | Intra- individual CVs (%) |
Inter- individual CVs (%) |
|
| Raw GABA+ | 1.64 ± 0.39 | 12.0 ± 3.7 | 23.6 | 2.24 ± 0.32 | 4.7 ± 3.1 | 14.2 | 1.86 ± 0.32 | 5.0 ± 3.7 | 17.3 | 2.40 ± 0.34 | 8.7 ± 4.3 | 14.1 |
| Corrected GABA+ | 1.05 ± 0.25 | 11.9 ± 4.1 | 23.9 | 1.44 ± 0.21 | 5.3 ± 2.9 | 14.4 | 1.15 ± 0.20 | 5.0 ± 3.7 | 17.6 | 1.49 ± 0.21 | 8.5 ± 3.7 | 14.1 |
| Raw GABA+/Cr | 0.17 ± 0.04 | 13.9 ± 6.9 | 25.6 | 0.23 ± 0.03 | 6.6 ± 5.0 | 14.5 | 0.19 ± 0.05 | 6.9 ± 7.0 | 27.0 | 0.25 ± 0.05 | 9.5 ± 2.5 | 21.3 |
| Corrected GABA+/Cr | 0.22 ± 0.05 | 13.4 ± 6.3 | 24.2 | 0.30 ± 0.04 | 6.1 ± 4.8 | 13.7 | 0.25 ± 0.05 | 5.0 ± 2.9 | 20.9 | 0.32 ± 0.05 | 8.0 ± 3.6 | 16.4 |
| Raw GABA+/NAA | 0.15 ± 0.03 | 9.4 ± 7.3 | 20.4 | 0.21 ± 0.03 | 5.1 ± 3.5 | 13.2 | 0.17 ± 0.02 | 7.9 ± 5.1 | 14.8 | 0.22 ± 0.03 | 9.8 ± 8.6 | 14.1 |
| Corrected GABA+/NAA | 0.24 ± 0.05 | 11.5 ± 4.2 | 22.1 | 0.33 ± 0.04 | 4.4 ± 2.8 | 12.6 | 0.27 ± 0.05 | 4.0 ± 2.8 | 18.1 | 0.35 ± 0.05 | 9.3 ± 5.9 | 15.6 |