Table 3.
Raw and corrected mean metabolite levels in institutional units obtained from short-TE spectra using LCModel from all subjects, and corresponding intra-individual and inter-individual coefficients of variation (CVs).
| Left Cerebellar Dentate | Right Cerebellar Dentate |
Left Cerebellar Cortex | Right Cerebellar Cortex | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Levels | Intra- individual CVs (%) |
Inter- individual CVs (%) |
Levels | Intra- individual CVs (%) |
Inter- individual CVs (%) |
Levels | Intra- individual CVs (%) |
Inter- individual CVs (%) |
Levels | Intra- individual CVs (%) |
Inter- individual CVs (%) |
|
| Raw Cr | 7.00 ± 0.77 | 2.8 ± 2.1 | 10.9 | 6.95 ± 0.62 | 3.4 ± 2.3 | 9.0 | 8.09 ± 0.68 | 2.9 ± 1.6 | 8.3 | 7.62 ± 0.58 | 1.2 ± 0.8 | 7.6 |
| Corrected Cr | 4.87 ± 0.61 | 3.0 ± 1.7 | 12.6 | 4.65 ± 0.50 | 3.2 ± 2.0 | 10.7 | 5.57 ± 0.76 | 4.6 ± 1.9 | 9.9 | 5.16 ± 0.57 | 4.4 ± 4.4 | 11.1 |
| Raw NAA | 6.79 ± 0.32 | 1.3 ± 0.6 | 4.7 | 6.97 ± 0.47 | 3.4 ± 2.0 | 6.7 | 6.83 ± 0.42 | 2.6 ± 1.4 | 6.1 | 5.40 ± 0.26 | 1.2 ± 0.6 | 4.8 |
| Corrected NAA | 4.35 ± 0.17 | 1.3 ± 0.5 | 4.0 | 4.31 ± 0.33 | 3.7 ± 2.0 | 7.6 | 4.34 ± 0.36* | 3.0 ± 1.5 | 8.2 | 3.37 ± 0.25* | 4.3 ± 3.2 | 7.3 |
| Corrected NAA/Cr | 0.91 ± 0.11 | 2.1 ± 2.5 | 12.1 | 0.93 ± 0.09 | 5.4 ± 3.0 | 10.1 | 0.78 ± 0.07 | 3.0 ± 1.4 | 8.4 | 0.66 ± 0.06 | 1.5 ± 1.0 | 8.4 |
| Raw Glu | 5.53 ± 0.79 | 3.7 ± 2.9 | 14.3 | 5.99 ± 0.93 | 5.8 ± 2.9 | 15.5 | 6.60 ± 0.69 | 5.5 ± 4.6 | 10.5 | 5.67 ± 0.50 | 4.4 ± 0.7 | 8.9 |
| Corrected Glu | 3.73 ± 0.50 | 3.4 ± 2.4 | 13.5 | 3.89 ± 0.60 | 5.4 ± 3.0 | 15.4 | 4.40 ± 0.43 | 4.6 ± 4.4 | 9.8 | 3.72 ± 0.41 | 5.5 ± 0.5 | 11.1 |
*
p<0.01 when comparing left versus right cerebellar cortex.