Table 1.
Postnatal Phenotypes
| A: WT Male x Het Female | ||||
|---|---|---|---|---|
| Litter | WT Male | KO Male | WT Female | Het (Xm-X) |
| 1 | 4 | 1 | 5 | 0 |
| 2 | 2 | 1 | 1 | 3 |
| 3 | 2 | 1 | 2 | 0 |
| 4 | 1 | 1 | 4 | 2 |
| 5 | 2 | 0 | 2 | 0 |
| 6 | 5 | 0 | 0 | 2 |
| 7 | 1 | 0 | 3 | 1 |
| 8 | 2 | 0 | 1 | 3 |
| 9 | 6 | 0 | 2 | 0 |
| 10 | 2 | 0 | 0 | 1 |
| 11 | 2 | 0 | 0 | 3 |
| 12 | 3 | 0 | 0 | 3 |
| 13 | 3 | 0 | 3 | 0 |
| 14 | 4 | 0 | 2 | 2 |
| 15 | 4 | 0 | 2 | 2 |
| 16 | 1 | 0 | 1 | 1 |
| 17 | 3 | 0 | 4 | 0 |
| 18 | 5 | 0 | 2 | 0 |
| 19 | 3 | 0 | 4 | 1 |
| 20 | 2 | 0 | 1 | 3 |
| 21 | 2 | 0 | 2 | 1 |
| 22 | 3 | 1 | 2 | 0 |
| 23 | 3 | 0 | 3 | 0 |
| Actual # Offspring | 59 | 7* | 46 | 24 |
| Expected # Offspring | 34 | 34 | 34 | 34 |
| B: KO Male x Het Female | ||||
|---|---|---|---|---|
| Litter | WT Male | KO Male | KO Female | Het (XXp-) |
| 1 | 0 | 1 | 0 | 3 |
| 2 | 1 | 0 | 0 | 3 |
| 3 | 0 | 1 | 0 | 0 |
| Actual #Offspring | 1 | 2 | 0 | 6 |
| Expected #Offspring | 2–3 | 2–3 | 2–3 | 2–3 |
*
Statistically significant deviation from the expected number of offspring