Table 2.
Prenatal Genotypes
| A: WT Male x Het Female | ||||
|---|---|---|---|---|
| Litter | WT Males | KO Male | WT Female | Het (Xm-X) |
| e12.5-L1 | 1 | 0 | 2 | 3 |
| e12.5-L2 | 1 | 1 | 1 | 3 |
| e15.5-L3 | 0 | 0 | 3 | 3 |
| e15.5-L4 | 2 | 1 | 2 | 1 |
| e16.5-L5 | 3 | 0 | 1 | 3 |
| e16.5-L6 | 2 | 0 | 1 | 4 |
| e17.5-L7 | 1 | 3 | 3 | 2 |
| e18.5-L8 | 3 | 1 | 1 | 2 |
| e18.5-L9 | 3 | 2 | 2 | 0 |
| Actual # Offspring | 16 | 8 | 16 | 21 |
| Expected # Offspring | 15–16 | 15–16 | 15–16 | 15–16 |
| B: KO Male x Het Female | ||||
|---|---|---|---|---|
| Litter | WT Male | KO Male | KO Female | Het (XXp-) |
| e16.5-L1 | 3 | 3 | 1 | 1 |
| e17.5-L2 | 3 | 1 | 2 | 2 |
| e18.5-L3 | 1 | 1 | 0 | 0 |
| e16.5-18.5-L4 | 3 | 2 | 2 | 2 |
| Actual # Offspring | 10 | 7 | 5 | 5 |
| Expected # Offspring | 6–7 | 6–7 | 6–7 | 6–7 |