Table 5.
Correlation Coefficients for Mitochondrial Measures and Glucose/Insulin for All Participants and Split by Gender
| Both Genders | Female | Male | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Pearson | Partial (BMI) | Partial (BMI + gender) | Partial (BMI + gender + age) | Pearson | Partial (BMI) | Partial (BMI + age) | Pearson | Partial (BMI) | Partial (BMI + age) | |
| Citrate Synthase Associations | ||||||||||
| HOMA-IRa | 0.21 | 0.57** | 0.55* | 0.58** | 0.08 | 0.62* | 0.61 | 0.26 | 0.46 | 0.53 | 
| Insulin (mIU/L)a | 0.20 | 0.66*** | 0.63** | 0.60** | 0.09 | 0.71* | 0.63 | 0.25 | 0.49 | 0.51 | 
| Glucose (mmol/L) | 0.19 | 0.31 | 0.25 | 0.34 | 0.09 | 0.58 | 0.61 | 0.18 | 0.05 | 0.44 | 
| State 3 OCR Associations | ||||||||||
| HOMA-IRa | −0.19 | −0.27 | −0.32 | −0.12 | −0.53 | −0.45 | −0.39 | −0.08 | −0.05 | 0.20 | 
| Insulin (mIU/L)a | −0.19 | −0.24 | −0.31 | −0.13 | −0.51 | −0.43 | −0.39 | 0.08 | 0.00 | 0.19 | 
| Glucose (mmol/L) | −0.07 | −0.22 | −0.30 | −0.02 | −0.35 | −0.22 | −0.17 | −0.05 | −0.58 | 0.14 | 
| State 4o OCR Associations | ||||||||||
| HOMA-IRa | −0.27 | −0.39 | −0.39 | −0.16 | −0.54 | −0.53 | −0.45 | −0.06 | −0.21 | 0.10 | 
| Insulin (mIU/L)a | −0.27 | −0.36 | −0.36 | −0.16 | −0.52 | −0.52 | −0.46 | −0.05 | −0.15 | 0.10 | 
| Glucose (mmol/L) | −0.21 | −0.38 | −0.38 | −0.07 | −0.33 | −0.26 | −0.18 | −0.20 | −0.72* | 0.01 | 
BMI body mass index, HOMA-IR homeostatic model assessment of insulin resistance, OCR oxygen consumption rate
aVariables were square-root-transformed to achieve normal distribution
* = p ≤ 0.05, ** = p ≤ 0.01, *** = p ≤ 0.001
Females: N = 12, Males: N = 11-13