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. 2015 Oct 6;6:194. doi: 10.1186/s13287-015-0185-z

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© Pacioni et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Orthotopic brain tumor xenograft. Cherry-U87MG cells and GFP-MSCs, either unloaded or loaded with PTX, were grafted in the right striatum of immunosuppressed rats. The two cell lines were injected into distinct brain sites (a). Low-power picture of a coronal section through the injection sites of GFP-MSCs showing their migration towards the Cherry-U87MG cells. Scale bar = 250 μm (b). High-power pictures showing the red tumor that appears to be massively colonized by the green MSCs. Scale bars = 40 μm (c). GFP green fluorescent protein, MSC mesenchymal stem/stromal cell