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. 2015 Oct 6;10(10):e0139149. doi: 10.1371/journal.pone.0139149

Fig 6. MOLF mice showed exacerbated AOM-induced CRC development.

Fig 6

[A] AOM was intraperitonally injected into 6 months old B6 (n = 7) and MOLF (n = 7) mice once a week for 6 weeks and sacrificed after addition 8 weeks. Body weight was measure weekly as shown. [B] AOM-treated B6 and MOLF mice colons were open-up longitudinally and inspected. [C] Tumor size and multiplicity of colons from steady state or AOM-treated B6 and MOLF mice were determined under a dissection microscope (n = 7 in each group). [D] Representative H&E section of colons from AOM-treated B6 and MOLF mice are shown. [E] Histological scoring of tumor from AOM-treated B6 (n = 7) and MOLF (n = 7) mice are shown. *P<0.05, **P<0.01, ***P<0.001 between the two groups as indicated.