Table 2.
Highly expressed genes in HEMs
| Gene Name (Gene ID) | Average FPKM ± SEM |
|---|---|
| premelanosome protein (PMEL17) | 8302.8 ± 2306.6 |
| tyrosinase-related protein 1 (TYRP1) | 7481.6 ± 882.4 |
| eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) | 3172.8 ± 734.0 |
| vimentin (VIM) | 2912.1 ± 526.4 |
| ferritin, heavy polypeptide (FTH1) | 2536.3 ± 416.5 |
| CD63 molecule (CD63) | 2355.4 ± 229.4 |
| ferritin, light polypeptide (FTL) | 1848.3 ± 268.5 |
| glycoprotein (transmembrane) nmb (GPNMB) | 1795.5 ± 447.3 |
| tumor protein, translationally-controlled 1(TPT1) | 1722.7 ± 362.5 |
| Prosaposin (PSAP) | 1682.8 ± 327.1 |
| ATPase, Na+/K+ transporting, alpha 1 polypeptide (ATP1A1) | 1628.1 ± 255.3 |
| tyrosinase-related protein 2 (TYRP2) | 1566.2 ± 538.9 |
| actin, gamma 1 (ACTG1) | 1562.1 ± 86.3 |
| melanoma antigen 1 (MLANA) | 1550.1 ± 244.1 |
| glyceraldehyde-3-phosphate dehydrogenase (GAPDH) | 1524.2 ± 141.1 |
| tyrosinase (TYR) | 1517.2 ± 65.0 |
| thymosin beta 10 (TMSB10) | 1367.6 ± 158.3 |
| eukaryotic translation elongation factor 1 gamma (EEF1G) | 1155.6 ± 157.7 |
| annexin A5 (ANXA5) | 1139.9 ± 93.8 |
| lectin, galactoside-binding, soluble, 3 (LGALS3) | 1087.2 ± 76.5 |
| spermidine/spermine N1-acetyltransferase 1 (SAT1) | 1033.1 ± 387.8 |
| lectin, galactoside-binding, soluble, 1 (LGALS1) | 1030.8 ± 63.7 |
| ubiquitin B (UBB) | 961.3 ± 161.7 |
| heat shock 70kDa protein 8 (HSPA8) | 944.6 ± 81.0 |
| cofilin 1 (non-muscle) (CFL1) | 922.6 ± 89.3 |
| ATP1A1 opposite strand (ATP1A1OS) | 853.4 ± 134.1 |
| actin, beta (ACTB) | 852.5 ± 140.8 |
| stearoyl-CoA desaturase (delta-9-desaturase) (SCD) | 848.4 ± 188.4 |
| TIMP metallopeptidase inhibitor 2 (TIMP2) | 835.1 ± 143.4 |
| G protein, beta polypeptide 2-like 1 (GNB2L1) | 813.6 ± 110.9 |
Highly expressed genes in melanocytes were obtained by averaging their FPKM from each library. For concision, ribosomal and non-coding genes we excluded from this table (their expression values can be found in Supplementary Table S1). Melanocyte specific pigmentation genes are highlighted in bold and, for comparison of expression levels, commonly used housekeeping genes (GAPDH and β-actin) are shown in dark grey background.