Table 2.
Changes in Edmonton Symptom Assessment Scale
| ESAS, average (SD) | Global symptom assessment | |||||||
|---|---|---|---|---|---|---|---|---|
| First clinic visit | Second clinic visit | Change* | Percentage change from first visit (%)* | P-value† | Better N (%) | Same N (%) | Worse N (%) | |
| Pain | 4.55 (3) | 3.79 (3) | 0.76 (3.01) | 17 | <0.0001 | 377 (47) | 251 (32) | 167 (21) |
| Fatigue | 4.93 (2.82) | 4.47 (2.92) | 0.46 (2.95) | 9 | <0.0001 | 293 (37) | 297 (37) | 206 (26) |
| Nausea | 1.72 (2.68) | 1.59 (2.53) | 0.14 (2.91) | 8 | 0.10 | 209 (26) | 460 (58) | 125 (16) |
| Depression | 2.55 (2.87) | 2.38 (2.83) | 0.18 (2.58) | 7 | 0.02 | 169 (21) | 494 (62) | 132 (17) |
| Anxiety | 3.18 (3.11) | 2.82 (2.9) | 0.36 (2.78) | 11 | 0.0002 | 191 (24) | 472 (59) | 131 (16) |
| Drowsiness | 3.31 (2.99) | 3.26 (2.88) | 0.05 (3.08) | 2 | 0.31 | 217 (27) | 410 (52) | 169 (21) |
| Poor appetite | 4.01 (3.03) | 3.85 (3.06) | 0.15 (3.16) | 4 | 0.09 | 267 (34) | 353 (44) | 176 (22) |
| Poor well being | 4.41 (2.76) | 4.12 (2.74) | 0.29 (2.92) | 7 | 0.002 | 293 (37) | 328 (41) | 174 (22) |
| Dyspnea | 2.51 (2.89) | 2.23 (2.81) | 0.27 (2.42) | 11 | 0.0008 | 155 (19) | 533 (67) | 108 (14) |
| Poor sleep | 4.08 (3.06) | 3.46 (2.85) | 0.62 (3.13) | 15 | <0.0001 | 258 (32) | 410 (52) | 128 (16) |
*
improvement is indicated by a positive value
†
paired t-test was used to determine the difference in ESAS scores between first and second study visit