Table 2. Inhibition of BoNT/E3 endopeptidase activity.
scFv | Antibody concentration for 50% endopeptidase inhibition (IC50) [nM] | Molar ratio scFv:toxin |
---|---|---|
ELC18 | 112.8 | 49,214 |
ELC51 | 58.6 | 25,571 |
ELC76 | 33.8 | 14,765 |
ELC77 | 49.1 | 21,428 |
scFv | Antibody concentration for 50% endopeptidase inhibition (IC50) [nM] | Molar ratio scFv:toxin |
---|---|---|
ELC18 | 112.8 | 49,214 |
ELC51 | 58.6 | 25,571 |
ELC76 | 33.8 | 14,765 |
ELC77 | 49.1 | 21,428 |