Table 5. Ex vivo phrenic nerve-hemidiaphragm assay.
Neutralization of BoNT/E3 toxicity (20LD50/mL) by the BoNT/E3 specific ELC18 as scFv at different concentrations.
| ELC18 (scFv) | 50% paralysis time [min] |
|---|---|
| 165 nM | 445 |
| 16.5 nM | 290 |
| 3.3 nM | 291 |
| 0.3 nM | 164 |
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