Table 8. GMT for ELISA and PRNT at all post-baseline visits (FAS, N = 632).
| Week | Diagnosed AD (N = 350) GMT (95% CI) | Healthy (N = 282) GMT (95% CI) | Ratio of GMTs (95% CI) (AD / Healthy) |
|---|---|---|---|
| ELISA | |||
| Week 0 | 1.7 (1.5, 2.0) | 1.4 (1.2, 1.6) | 1.211 (0.984, 1.489) |
| Week 1 | 3.4 (2.7, 4.3) | 2.5 (2.0, 3.1) | 1.387 (1.004, 1.916) |
| Week 4 | 59.7 (49.2, 72.4) | 59.7 (48.8, 73.1) | 0.999 (0.755, 1.324) |
| Week 6 | 516.0 (449.7, 592.0) | 508.8 (432.2, 598.9) | 1.014 (0.821, 1.253) |
| Week 8 | 285.8 (247.6, 329.8) | 283.8 (240.8, 334.6) | 1.007 (0.811, 1.251) |
| Week 32 | 30.0 (21.0, 42.7) | 22.8 (16.0, 32.4) | 1.314 (0.798, 2.163) |
| PRNT | |||
| Week 0 | 1.2 (1.1, 1.3) | 1.1 (1.0, 1.2) | 1.103 (0.982, 1.238) |
| Week 1 | 1.4 (1.2, 1.7) | 1.3 (1.1, 1.5) | 1.121 (0.924, 1.359) |
| Week 4 | 2.6 (2.1, 3.1) | 2.2 (1.9, 2.7) | 1.444 (0.868, 1.508) |
| Week 6 | 43.0 (35.0, 52.8) | 35.5 (28.1, 44.7) | 1.213 (0.890, 1.653) |
| Week 8 | 19.7 (15.9, 24.3) | 14.8 (11.8, 18.6) | 1.329 (0.971, 1.819) |
| Week 32 | 2.4 (1.8, 3.3) | 2.3 (1.7, 3.0) | 1.074 (0.713, 1.618) |
N = number of subjects in the specified group.