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. 2015 Oct 5;15:198. doi: 10.1186/s12866-015-0534-1

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© Silbereisen et al. 2015

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Comparison of the sensitivity of the bead-based Luminex immunoassay (a) and the corresponding antigen capture ELISA (b). Assay sensitivities were determined by analysing serial dilutions of inactivated B. melitensis (16 M, γ), B. abortus (544, γ) and B. suis (1330, formalin) cells. Dashed lines indicate the assay dependent limit of detection (LOD) defined as mean blank (i.e. the no-antigen control) plus three times the standard deviation (SD)