Table 3.
Results of univariable and multivariable logistic regression analyses of risk factors for BFR in autologous bone flaps
| Variable | No BFR (n = 57) | BFR (n = 14) | Univariable OR (95 % CI) | Multivariable OR (95 % CI) |
|---|---|---|---|---|
| p-value | p-value | |||
| Median age (range) (yrs) | 38 (14-65) | 26.5 (1.0-60) | 0.96 (0.92-1.00) | 0.94 (0.88-1.0) |
| 0.065 | 0.04 | |||
| Gender - n male | 36 | 9 | 0.95 (0.28-3.22) | |
| 0.94 | ||||
| Preceding pathology* -n | ||||
| - Trauma | 48 | 10 | 0.47 (0.12-1.83) | |
| - Stroke | 9 | 4 | 0.28 | |
| Surgery prior to DC | 31/26 | 8/6 | 1.03 (0.63-1.68) | |
| (yes/no) | 0.92 | |||
| Fragmentation -n | 8 | 7 | 6.13 (1.69-22.2) | 14.3 (2.26-89) |
| 0.006 | 0.005 | |||
| Median operating time (min) (range) | 81.5 (35-390) | 72.5 (51-164) | 0.99 (0.98-1.00) | |
| 0.27 | ||||
| GOS at time of CP | ||||
| 2 | 14 | 0 | 2.2 (1.16-4.20) | 2.55 (1.04-6.23) |
| 3 | 19 | 4 | 0.02 | 0.04 |
| 4 | 14 | 4 | ||
| 5 | 10 | 6 | ||
| Median time DC-CP (range) (days) | 70 (19-171) | 88 (48-353) | 1.02 (1.00-1.03) | 1.03 (1.00-1.04) |
| 0.02 | 0.02 | |||
| Median GCS prior to DC | 6 | 8 | 1.12 (0.95-1.32) | |
| 0.19 | ||||
| Registered co-morbidity -n | 13 | 4 | 1.01 (0.77-1.32) | |
| 0.93 | ||||
| VP-shunt at time of CP -n | 5 | 2 | 1.73 (0.30-10.0) | |
| 0.54 | ||||
DC decompressive craniectomy, CP cranioplasty, GCS Glasgow Coma Scale, VP ventriculoperitoneal, BFR bone flap resorption
*Trauma modeled as the reference category in the univariable analysis