Table 2.

Ivermectin pharmacokinetic parameters in dogs following oral administration (0.3 mg/kg BW) alone or concurrently with fluralaner (56 mg/kg BW)

Parameter	Unit	Ivermectin	Ivermectin plus Fluralaner	P-value
		Mean ± SD	Mean ± SD
Cmax	(ng/mL)	92.70 ± 26.77	80.52 ± 21.41	0.2465
tmax	(day)	0.29 ± 0.10	0.31 ± 0.11	0.7269
AUC∞	(day*ng/mL)	141.96 ± 27.23	134.26 ± 37.99	0.5073
t½	(days)	2.07 ± 0.71	1.84 ± 0.42	0.4888

SD standard deviation