Table 5.
Sensitivity and Specificity of verbal autopsy against clinical diagnosis
Cause of neonatal deaths | True positive | False positive | True negative | False negative | Sensitivity | Specificity | PPV | NPV | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
value | value | value | value | % | [95 % CI] | % | [95 % CI] | % | [95 % CI] | % | [95 % CI] | |
Congenital malformations | 8 | 5 | 607 | 6 | 57.1 | 32.6–78.6 | 99.2 | 98.1–99.6 | 61.5 | 35.5, 82.3 | 99.0 | 97.9, 99.5 |
Immaturity [<33 wks] | 209 | 20 | 382 | 15 | 93.3 | 89.2–95.9 | 95.0 | 92.4–96.7 | 91.3 | 86.9, 94.3 | 96.2 | 93.8, 97.7 |
Birth asphyxia | 147 | 41 | 409 | 29 | 83.5 | 77.3–88.3 | 90.9 | 87.8–93.2 | 78.2 | 71.8, 83.5 | 93.4 | 90.6, 95.3 |
Tetanus | 6 | 3 | 614 | 3 | 66.7 | 35.4–87.9 | 99.5 | 98.6–99.8 | 66.7 | 35.4, 87.9 | 99.5 | 98.6, 99.8 |
Severe infectiona | 138 | 27 | 424 | 37 | 78.9 | 72.2–84.3 | 94.0 | 91.4–95.9 | 83.6 | 77.2, 88.5 | 92.0 | 89.1, 94.1 |
aSevere infection included Sepsis, Meningitis, Pneumonia & Diarrhea
PPV Positive Predictive Value
NPV Negative Predictive Value