Fig. 8.

Genes activated with PHTF1 overexpression. a Expression level of BCL11B, FEM1b and Apaf-1 in Jurkat cells after PHTF1 overexpression by transduction with PHTF1 lentivirus (PHTF1) or in the presence of control lentivirus (CON 2). The BCL11B expression level was unchanged versus control; FEM1b and Apaf-1 were up-regulated 2.4- and 4.4-fold, respectively, versus control. Data shown are the mean ± SEM (n = 3), P = 0.007 for bar 3 versus bar 4; P = 0.009 for bar 5 versus bar 6. b Expression levels of BCL11B, FEM1b and Apaf-1 in Molt-4 cells after PHTF1 overexpression by PHTF1 lentivirus (PHTF1) or control lentivirus (CON 2). The BCL11B expression level was unchanged versus control; FEM1b and Apaf-1 were up-regulated 6.3- and 29.4-fold, respectively, versus control. Data shown are the mean ± SEM (n = 3), P = 0.020 for bar 3 versus bar 4; P = 0.005 for bar 5 versus bar 6