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. 2015 Oct 6;10(10):e0139886. doi: 10.1371/journal.pone.0139886

Table 2. Univariate and multivariate analyses of risk factors associated with all-cause mortality and sudden cardiac death using a Cox proportional hazards model in 312 hemodialysis patients.

All-cause mortality Sudden cardiac death
Unadjusted Adjusted Unadjusted Adjusted
HR (95% CI) aHR (95% CI) HR (95% CI) aHR (95% CI)
Age 1.07 (1.05–1.09)* 1.05 (1.02–1.08)* 1.08 (1.05–1.12)* 1.07 (1.03–1.12)*
Female gender 0.83 (0.52–1.32) 1.38 (0.75–2.54) 0.93 (0.46–1.89) 0.93 (0.35–2.48)
Dialysis vintage 1 (0.99–1) 1 (1–1.006) 1 (0.99–1.01) 1.01 (1–1.02)
Body mass index 1 (0.93–1.08) 0.95 (0.87–1.03) 1.05 (0.95–1.17) 1.04 (0.9–1.2)
1.0 mEq/L K dialysate 0.17 (0.08–0.36)* 0.16 (0.07–0.37)* 0.41 (0.17–0.95)* 0.33 (0.13–0.85)*
2.5 mEq/L Ca dialysate 0.6 (0.19–1.9) 0.70 (0.21–2.3) 1.37 (0.42–4.55) 1.82 (0.5–6.6)
CAD 2.92 (1.51–5.67)* 1.89 (0.88–4.07) 2.9 (0.98–8.56) 1.7 (0.47–6.08)
DM 3.33 (2.09–5.31)* 2.09 (1.14–3.83)* 5.12 (2.47–10.6)* 4.68 (1.72–12.71)*
Kt/V 0.26 (0.08–0.85)* 0.05 (0.01–0.26)* 0.44 (0.08–2.56) 0.21 (0.01–4.4)
Serum albumin 0.07 (0.03–0.13)* 0.16 (0.06–0.4)* 0.08 (0.03–0.23)* 0.19 (0.04–1.01)
Hemoglobin 0.77 (0.62–0.97)* 0.79 (0.61–1.02) 0.99 (0.7–1.38) 0.97 (0.64–1.47)
Serum K concentration
 Serum K < 4 mEq/L 3.82 (1.5–9.7)* 1.92 (0.67–5.5) 5.37 (1.22–23.65)* 2.82 (0.52–15.4)
 Serum K 4–5 mEq/L 1.00 (Reference) 1.00 (Reference) 1.00 (Reference) 1.00 (Reference)
 Serum K >5 mEq/L 0.67 (0.37–1.21) 2.1 (1.08–4.09)* 1.32 (0.62–2.85) 4.11 (1.62–10.41) *
Serum creatinine 0.69 (0.61–0.79)* 0.98 (0.78–1.22) 0.66 (0.54–0.81)* 0.93 (0.65–1.34)
Serum phosphate 0.64 (0.5–0.83)* 0.91 (0.64–1.29) 0.78 (0.53–1.16) 1.14 (0.67–1.94)
ALP 1 (1–1.002) 1 (1–1.006) 1 (1–1.004) 1 (1–1.008)

Abbreviations: HR, hazard ratio; aHR, adjusted hazard ratio; CI, confidence interval; K, potassium; Ca, calcium; CAD: Coronary artery disease; DM: Diabetes mellitus; ALP: Alkaline phosphatase.

*p value < 0.05.