Table 2. Clinical and Biochemical Characteristics of Elderly Prediabetic Subjects with and without Metabolic Syndrome.
| Characteristic | Non-MetS | MetS |
|---|---|---|
| No. of subjects | 85 | 35 |
| Age, yr | 67.33±1.91 | 66.89±1.51 |
| BMI, kg/m2 | 23.16±2.59 | 27.08±2.58b |
| WC, cm | 78.61±6.85 | 91.67±3.84b |
| HC, cm | 90.42±5.68 | 98.49±4.69b |
| Waist-to-hip ratio | 0.87±0.04 | 0.93±0.04b |
| Total body fat, kg | 16.01±5.58 | 21.91±4.20b |
| Visceral fat, kg | 1.98±0.70 | 3.29±0.67b |
| Total body fat ratio | 27.43±6.95 | 31.20±6.44b |
| Visceral fat ratio | 10.51±2.40 | 13.86±1.64b |
| Total muscle, kg | 37.87±5.74 | 44.84±7.50b |
| Fasting glucose, mmol/L | 5.30±0.50 | 5.56±0.62a |
| 2-Hour glucose, mmol/L | 8.11±1.66 | 8.09±1.94 |
| Fasting insulin, pmol/L | 56.39±27.15 | 83.62±47.16b |
| 2-Hour insulin, pmol/L | 305.72±211.27 | 498.65±419.96b |
| HbA1c, % | 5.62±0.36 | 5.65±0.37 |
| HOMA-IR index | 1.92±0.96 | 3.04±1.91b |
| QUICKI | 0.35±0.02 | 0.33±0.02b |
| TC, mmol/L | 5.70±1.01 | 5.76±1.00 |
| TG, mmol/L | 1.89±1.14 | 2.41±1.25a |
| HDL-C, mmol/L | 1.21±0.31 | 1.13±0.20 |
| LDL-C, mmol/L | 3.42±0.83 | 3.39±0.85 |
| Adiponectin, µg/mL | 11.10±4.62 | 8.61±3.48a |
| PWV, m/sec | 16.31±3.55 | 15.71±3.00 |
| SBP, mm Hg | 136.20±17.05 | 138.49±15.60 |
| DBP, mm Hg | 84.36±10.15 | 89.23±9.40 |
| AST, U/L | 28.56±10.39 | 31.08±10.07 |
| ALT, U/L | 23.44±10.15 | 33.88±13.91b |
| γ-GTP, U/L | 26.23±23.25 | 53.60±65.65a |
| hs-CRP, mg/dL | 1.82±3.52 | 2.37±4.57 |
| Ferritin, µg/L | 87.33±87.53 | 138.71±111.95b |
Values are expressed as mean±SD. Two-hour glucose and 2-hour insulin represent glucose and insulin levels at 120 minutes after a glucose challenge.
MetS, metabolic syndrome; BMI, body mass index; WC, waist circumference; HC, hip circumference; HbA1c, glycated hemoglobin; HOMA-IR, homeostasis model assessment of insulin resistance; QUICKI, quantitative insulin sensitivity check index; TC, total cholesterol; TG, triglyceride; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; PWV, pulse-wave velocity; SBP, systolic blood pressure; DBP, diastolic blood pressure; AST, aspartate aminotransferase; ALT, alanine aminotransferase; γ-GTP, gamma-glutamyl transpeptidase; hs-CRP, high-sensitivity C-reactive protein.
aP<0.05 vs. non-MetS; bP<0.01 vs. non-MetS.