Fig. 3.

Default-mode network (DMN) connectivity differences among different patients sub-groups and healthy controls. (A). The mean FC values extracted from the frontal regions in the diabetic group were significantly higher than the control group, while the mean FC values of the occipital lobe were significantly lower. There is a trend that patients with insulin treatment suffered more functional alterations than those without, although the differences were not significant. (B) The mean FC value extracted from the frontal and the occipital lobe did not differ between the patients with and without diabetic complications. FC, functional connectivity; RSFG, right superior frontal gyrus; LSFG, left superior frontal gyrus; PCC, posterior cingulate cortex