Table 2.
Histologic characteristics of mastectomy specimens for ductal carcinoma in situ (DCIS) diagnosed on vacuum-assisted biopsy (VAB) patients
| bDCIS (n = 196) | |
|---|---|
| SLN detected | 192 (98.5) |
| Negative SLN | 165 (85.9) |
| Positive SLN | 27 (14.1) |
| 1 Positive SLN | 20 (74.1) |
| 2 Positive SLNs | 6 (22.2) |
| 3 or 4 Positive SLNs | 1 (3.7) |
| Mastectomy histologic results | |
| pT0 | 3 (1.5) |
| pT is (pure mDCIS) | 117 (59.7) |
| pT1 mic (mDCIS–MI) | 20 (10.3) |
| pT ≥ 1a (mDCIS–IDC) | 56 (28.5) |
| mDCIS nuclear grade | |
| Low | 14 (7.1) |
| Intermediate | 72 (36.7) |
| High | 101 (51.6) |
| Missing | 9 (4.6) |
| Necrosis (mDCIS) | |
| No | 35 (17.9) |
| Yes | 152 (77.5) |
| Missing | 9 (4.6) |
| Inflammation | |
| No | 43 (22) |
| Yes | 144 (73.4) |
| Missing | 9 (4.6) |
| DCIS size: mm (range) | 69.3 (4–180) |
| Invasive component (for IDC) | 56 (100) |
| Unifocal | 30 (57.7) |
| Multifocala | 22 (23.1) |
| Missing | 4 (19.2) |
| Histological subtype | 56 (100) |
| IDC | 53 (94.6) |
| Others | 3 (5.4) |
| Size (invasive): mm (range) | 9.3 (1–45) |
| pT1 | 50/56 (89.3) |
| IDC grade | 56 (100) |
| 1 | 15 (21.4) |
| 2 | 24 (42.9) |
| 3 | 16 (28.6) |
| Missing | 4 (7.1) |
bDCIS vacuum-assisted biopsy-diagnosed ductal carcinoma in situ, VAB vacuum-assisted biopsy, n number of patients, SLN sentinel lymph node, mDCIS mastectomy-diagnosed ductal carcinoma in situ, mDCIS-MI mastectomy-diagnosed ductal carcinoma in situ with microinvasion, IDC invasive ductal carcinoma, mDCIS-IDC mastectomy-diagnosed ductal carcinoma in situ with associated invasive carcinoma
aMultifocal was defined as 2 or more foci of invasive carcinoma separated by at least 2 mm