Protein expression of select inflammatory mediators in sinonasal tissues. Protein levels of (A) eosinophil cationic protein (ECP), (B) IL-13, (C) eotaxin-2, (D) monocyte chemoattractant protein (MCP)-4, (E) regulated upon activation, normal T-cell expressed and secreted protein (RANTES), and (F) IFN-γ were measured in uncinate tissue (UT) of healthy controls, UT of patients with chronic rhinosinusitis without nasal polyps (CRSsNP), and UT and nasal polyps of patients with chronic sinusitis with nasal polyps (CRSwNP). Statistical significance (P < 0.05) was determined by Kruskal-Wallis test with post hoc analysis using Dunn’s test for multiple comparison. Dot plots illustrate individual data points, and solid lines represent the mean ± SEM. Concentrations of ECP were expressed as nanograms per milligram of tissue, and all other mediators are expressed as picograms per milligram of tissue.