Table 4.
IFN Relative Gene Expression in Sinonasal Tissues
| Control UT (Mean ± SEM) | CRSsNP UT (Mean ± SEM) | CRSwNP UT (Mean ± SEM) | CRSwNP Polyp (Mean ± SEM) | |
|---|---|---|---|---|
| IFN-α2 | 8.5 ± 3.5 | 7.5 ± 3.3 | 5.3 ± 1.6 | 8.3 ± 3.2 |
| IFN-α4 | 2.7 ± 0.9 | 4.8 ± 3.3 | 2.3 ± 1.4 | 4.3 ± 3.2 |
| IFN-α5 | 8.3 ± 2.6 | 9.0 ± 3.5 | 15.5 ± 6.3 | 5.2 ± 1.7 |
| IFN-α6 | 7.8 ± 3.8 | 7.7 ± 4.1 | 19.8 ± 9.4 | 9.7 ± 3.4 |
| IFN-α7 | 7.5 ± 3.6 | 8.8 ± 3.7 | 15.5 ± 6.3 | 9.5 ± 4.3 |
| IFN-α8 | 1.0 ± 0.3 | 2.5 ± 1.3 | 6.8 ± 2.7 | 6.5 ± 1.6 |
| IFN-α10 | 5.2 ± 3.6 | 2.3 ± 0.6 | 6.3 ± 2.6 | 1.7 ± 0.3 |
| IFN-α13 | 9.3 ± 2.5 | 4.5 ± 1.0 | 5.1 ± 1.9 | 5.3 ± 2.1 |
| IFN-α14 | 4.7 ± 3.5 | 8.7 ± 2.9 | 4.0 ± 1.7 | 1.7 ± 0.3 |
| IFN-α16 | 5.3 ± 2.7 | 8.5 ± 4.0 | 9.0 ± 5.5 | 3.8 ± 2.2 |
| IFN-α17 | 6.3 ± 5.1 | 2.3 ± 0.7 | 5.0 ± 2.2 | 3.2 ± 1.0 |
| IFN-α21 | 8.0 ± 2.0 | 16.0 ± 4.6 | 10.5 ± 4.1 | 8.2 ± 2.4 |
| IFN-β1 | 10.3 ± 3.3 | 2.2 ± 0.4 | 1.3 ± 0.2 | 1.7 ± 0.7 |
| IFN-ε | 19.2 ± 5.2 | 24.0 ± 6.2 | 24.8 ± 8.0 | 24.3 ± 9.6 |
| IFN-κ | 4.5 ± 2.6 | 7.2 ± 3.0 | 7.7 ± 3.7 | 6.0 ± 1.8 |
| IFN-γ | 76.5 ± 31.9 | 129 ± 58.8 | 131 ± 46.3 | 78.2 ± 10.2 |
| IFN-ω | 8.0 ± 3.2 | 10.3 ± 3.4 | 8.3 ± 2.0 | 10.2 ± 4.0 |
| IFN-λ1 | 24.8 ± 2.2 | 15.7 ± 6.0 | 25.5 ± 6.3 | 36.8 ± 6.8 |
| IFN-λ2 | 7.3 ± 3.3 | 7.3 ± 2.4 | 13.8 ± 3.6 | 8.8 ± 3.1 |
| IFN-λ3 | 13.5 ± 2.8 | 11.2 ± 1.6 | 20.8 ± 7.9 | 10.5 ± 3.2 |
Definition of abbreviations: CRSsNP = chronic rhinosinusitis without nasal polyps; CRSwNP = chronic sinusitis with nasal polyps; UT = uncinate tissue.