Table 1.
Predicted Odds and Risk of Converting from Positive to Negative for Mycobacterium avium Complex by Early Semiquantitative Cultures, Symptom Presentation, and Radiologic Scores*
| Univariate Generalized Linear Models |
Univariate Logistic Regression Models |
|||||
|---|---|---|---|---|---|---|
| Variable | RR | 95% CI | P Value | OR | 95% CI | P Value |
| Culture results | ||||||
| Baseline culture | 1 | 0.90–1.02 | 0.2 | 0.8 | 0.6–1.0 | 0.2 |
| Culture Month 2 | 1.1 | 1.0–1.2 | 0.02 | 1.4 | 1.1–2.0 | 0.01 |
| Culture Month 3 | 1.2 | 1.1–1.4 | <0.0001 | 2.1 | 1.5–3.0 | <0.0001 |
| Change between baseline and Month 2 | 1.2 | 1.1–1.3 | <0.0001 | 6.9 | 2.9–16.6 | <0.0001 |
| Change between baseline and Month 3 | 1.2 | 1.1–1.3 | <0.0001 | 3.9 | 2.2–6.9 | <0.0001 |
| Symptoms | ||||||
| Improvement in cough between baseline and next clinical assessment | 1 | 1.002–1.004 | <0.0001 | 9.0 | 3.2–25.8 | <0.0001 |
| Radiology | ||||||
| Improvement in CXR between baseline and next clinical assessment | 1.3 | 1.2–1.5 | <0.0001 | 6.6 | 2.5–17.4 | 0.0001 |
| Improvement in CT between baseline and next clinical assessment | 2.3 | 1.5–3.5 | <0.0001 | 8.0 | 3.6–18.0 | <0.0001 |
Definition of abbreviations: CI = confidence interval; CT = computed tomography; CXR = chest X-ray; OR = odds ratio; RR = relative risk.
Results presented here are similar to those observed in multivariate models that included significant, uncorrelated variables from univariate models and were controlled for age and sex (multivariate results reported in text only and are not shown here for the sake of brevity).
Represents the risk of converting with each one-unit decrease in semiquantitative culture scores.