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. 2015 Sep 1;192(5):605–617. doi: 10.1164/rccm.201412-2141OC

Figure 2.

Figure 2.

Receiver operating characteristic curves and diagnostic performance of study assays in unexposed subjects and untreated patients with latent tuberculosis infection. (A) QuantiFERON TB Gold In-Tube (i.e., region of difference 1 [RD1] peptides). (B) Flow cytometry (FC) assay detection of percentage of CD25+CD134+ coexpression in RD1 antigen–stimulated CD3+CD4+ T cells. (C) FC assay detection of the percentage of CD25+CD134+ coexpression in purified protein derivative (PPD)-stimulated CD3+CD4+ T cells. (D) FC assay detection of percentage of CD25+CD134+ coexpression in RD1 antigen–stimulated CD3+CD8+ T cells. (E) FC assay detection of percentage of CD25+CD134+ coexpression in PPD-stimulated CD3+CD8+ T cells. (F) Diagnostic performance parameters of each test associated with the receiver operating characteristic analysis. Ag = antigen; AUC = area under the curve (i.e., diagnostic accuracy); nil = negative control.