Table 1.
Immune Gene Results
| Immune Variants | PNTM Affected (n) | PNTM Unaffected (n) | 1000G Control (n) |
|---|---|---|---|
| Samples with at least one PNTM-associated variant | 24 | 1 | 41 |
| Samples without a PNTM-associated variant* | 45 | 17 | 338 |
| Average number of variants per person† | 1.17 | 1.00 | 1.07 |
Definition of abbreviations: 1000G = 1000 Genomes Project; ND = not done, because there were too few samples in the unaffected family members of patients with pulmonary nontuberculous mycobacterial infection; PNTM = pulmonary nontuberculous mycobacterial infection.
*
PNTM affected versus PNTM unaffected, P = 0.02; PNTM unaffected versus 1000G control, not significant (P > 0.05); PNTM affected versus 1000G control, P = 2.5 × 10−6.
†
PNTM affected versus PNTM unaffected, ND; PNTM unaffected versus 1000G control, ND; PNTM affected versus 1000G control, not significant (P > 0.05).