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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Int J Obes (Lond). 2015 Apr 14;39(8):1292–1299. doi: 10.1038/ijo.2015.52

Figure 1. Time dependent expression of mIL-13 and its impact on body weight and energy intake of mice fed either regular or high fat diet.

Figure 1

(a) Serum level of IL13 in normal mice after hydrodynamic delivery of 1µg/animal of pLIVE-mIL13 plasmid; (b) body weight gain of animals over an 8-week period after hydrodynamic injection of 1µg/mouse of pLIVE-mIL13 fed an HFD (●) or pLIVE-GFP plasmids fed a regular chow (Δ) or HFD (■); (c) representative images of animals 8 weeks after gene transfer and fed with either a regular chow or an HFD; (d) body composition; and (e) weight of epididymal (EWAT), inguinal (IWAT) and perirenal (PRWAT) fat pad of animas at the end of 8-week on selected diets after plasmid transfer; and (f) average energy intake (kcal/mouse/day) of animas with gene transfer. Solid bars (■) represents animals injected with pLIVE-mIL13 plasmids and fed a HFD; open bars (□) represents animals injected with pLIVE-gfp plasmids and fed an HFD; and grey bars (■) represent animals injected with pLIVE-gfp and fed a regular chow. Data represent mean ± SEM (n=5). * P<0.05 compared with pGFP+HFD mice; **, P<0.05 compared to pGFP+HFD mice, and *** P<0.01 compared to pGFP+HFD mice.