Figure 2.

Haplotypes of probands with GNRHR R139H. In 10 probands (numbers 1, 3, 6–10, 12, 13, and 15), full phasing with both parents samples were possible and they shared common haplotypes. All probands were Caucasians, and eight of them (proband numbers 6–10, 12, 13, and 15) were from Poland. Blue horizontal lines display the individual haplotypes, with pink horizontal lines showing the haplotype regions identical with each other. The common minimum haplotype shared by all probands is marked with vertical dotted lines. In each of the probands homozygous for the mutation (subjects 8, 9, 12, 13, and 15), their two respective haplotypes are labeled a and b.