Table 1.

MAFs of Candidate Mutations for Haplotype Analyses

	Samples, n		IGD Patients		MAF From ExAc Browser
	Probands, n	Family Members, n	Screened Probands, n	MAF	European (Non-Finnish)	African	Total
GNRHR
Q106R	32	27	1098	0.016	0.004	0.0005	0.003
R262Q	12	10	1095	0.006	0.002	0.0003	0.002
R139H	15	11	1096	0.009	0.0002	0.0	0.0002
TACR3
W275X	7	3	760	0.004	0.0004	9.614 × 10−5	0.0002
PROKR2
R85H	3	1	1182	0.002	0.001	0.0003	0.0007
FGFR1
R250Q	5	1	1222	0.002	ND	ND	ND
G687R	4	1	1222	0.001	ND	ND	ND
HS6ST1
R382W	5	0	777	0.003	0.0005	0.0006	0.002
KAL1
R423X	8	2	1188	0.002	ND	ND	ND
R424X	6	1	1188	0.003	0	0	1.208 × 10−5
R457X	3	1	1189	0.002	ND	ND	ND

Abbreviation: ND, not detected.