Table 4.

OR (with 95% CI) for Type 2 Diabetes According to the Number of Exposures to Broad-Spectrum and/or Narrow-Spectrum Antibiotics Before Initiation of Type 2 Diabetes Treatment

	Broad Spectrum (0–1)	Broad Spectrum (2–4)	Broad Spectrum (≥5)
Narrow spectrum (0–1)	(Reference)	1.14 (1.09–1.19)	1.12 (1.01–1.25)
Narrow spectrum (2–4)	1.22 (1.20–1.24)	1.27 (1.23–1.31)	1.24 (1.17–1.32)
Narrow spectrum (≥5)	1.52 (1.49–1.55)	1.59 (1.55–1.63)	1.64 (1.59–1.69)

When exposure to narrow-spectrum antibiotics was held fixed, a relatively unchanged OR for type 2 diabetes was seen with increasing exposure to broad-spectrum antibiotics.