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. 2015 Oct 7;9:384. doi: 10.3389/fncel.2015.00384

Figure 7.

Figure 7

Arc immunoreactivity in newborn granule cells of control and SE rats with or without pentylenetetrazol (PTZ) treatment. Each GFP-labeled cell is indicated by two arrowheads in the middle panel. The scale bar (50 μm) applies to all panels. Note that Arc immunoreactivity in GFP-labeled cells is indistinguishable from surrounding granule cells in the same section. (A) In a PTZ-untreated control rat, Arc immunoreactivity is faint in the soma and dendrites of granule cells. (B) In a PTZ-untreated SE rat, Arc immunoreactivity became denser in the soma and apical dendrites of granule cells than that in PTZ-untreated controls, but the intensity of Arc immunoreactivity in the GFP-labeled cell is clearly indifferent from cells surrounding it. (C) Treatment with PTZ in a control rat increased Arc immunoreactivity in both the soma and apical dendrites of granule cells, including the GFP-labeled one. (D) Treatment with PTZ in an SE rat also increased Arc immunoreactivity in granule cells. However, Arc immunoreactivity in the GFP-labeled cell is similar to the vicinal granule cells unlabeled by GFP.