Table 1.
Characteristics of Cohort according to Self-reported Frailty.
| Cohort Characteristics | All N=1053 |
Frail N=808 |
Not Frail N=245 |
P-value |
|---|---|---|---|---|
| Sex, female | 45% (472) | 48.8% (394) | 31.8% (78) | <0.001 |
| Median Age, years | 63 (52,73) | 62.5 (52,73) | 65 (52,72) | 0.80 |
| Race | ||||
| African American | 26.8% (282) | 25.5% (206) | 31% (76) | 0.20 |
| Caucasian | 70.6% (743) | 71.7% (579) | 66.9% (167) | |
| Other | 2.7% (28) | 2.8% (23) | 2.0% (5) | |
| Comorbidities | ||||
| Diabetes mellitus | 58.5% (616) | 63% (509) | 43.7% (107) | < 0.001 |
| Heart Failure | 33.8% (356) | 36.4% (294) | 25.3% (62) | 0.001 |
| Atherosclerotic diseaseŦ | 37.9% (399) | 40.1% (324) | 30.6% (75) | 0.007 |
| BMI (kg/m2) | 29.6 (8.2) | 30.1 (8.26) | 28.1 (7.72) | <0 .001 |
| Laboratory Parameters | ||||
| Serum Albumin (g/dL) | 3.14 (0.7) | 3.13 (0.7) | 3.20 (0.70) | 0.30 |
| Hemoglobin (g/dL) | 10.1 (1.73) | 10.2 (1.74) | 9.94 (1.71) | 0.12 |
| Dialysis Related Parameters | ||||
| Dialysis Vintage (days) | 127[111,148] | 127 [112,149] | 127 [112,149] | 0.85 |
| Self-Reported Frailty Components | ||||
| Inactivity | 94% (985) | 99.6% (805) | 73.5% (180) | <0.001 |
| Poor Physical Function | 70.8% (746) | 91.5% (739) | 2.9% (7) | |
| Exhaustion | 51.1% (538) | 65.3% (528) | 4.1% (10) | |
*
Displayed as mean (standard deviation) for normally distributed variables, median [25th, 75th percentile] for non-normally distributed variables, and % (n) for categorical variables.
Ŧ
Atherosclerotic disease includes: coronary heart disease, cerebrovascular disease, peripheral vascular disease or amputation.