Figure 7.

ERK5 icKO mice do not display enhanced hypophagia behavior in a novelty-suppressed feeding test. After 4 d of food restriction, individually housed mice were introduced into an unfamiliar environment with one pellet of regular mouse food. A, Latency to eat the food pellet in the unfamiliar environment. B, Food consumption in the home cage. Once the mouse started eating the food or the 15 min time limit was reached, the mouse and a new preweighed food pellet were quickly transferred to the home cage and the food consumption in the next 5 min was measured. n.s., Not significant.