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. 2015 Mar 30;2(2):ENEURO.0009-15.2015. doi: 10.1523/ENEURO.0009-15.2015

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Copyright © 2015 Exton-McGuinness and Lee

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Combined infusion of AP-5/SCH23390 significantly impaired behavioral activity when administered immediately prior to the VR5 reactivation. A, Coinfusion of AP-5/SCH23390 (n = 6) significantly impaired lever pressing at test compared with PBS controls (n = 6). Infusions of MK-801 (n = 6), AP-5 (n = 5), or SCH23390 (n = 6) alone were without significant long-term effect on lever pressing. B, There was no significant evidence for any long-term impairment in nosepoking with any infusion. Data are represented as mean + SEM.