Table 1. MS-associated genes with significantly differential expressions in MS-related cells/tissue.
Sample | S1 | S2 | S3 | S4 | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Target cells/tissue | PBMC | CD34+ HPC | CD8+ T lymphocytes | Spinal cord | ||||||||
Sample size | 12:15 | 8:5 | 4:4 | 8:8 | ||||||||
Platform | [HG-U133_Plus_2] Affymetrix Human | Agilent-014850 Whole Human | [HG-U133_Plus_2] Affymetrix Human | [HG-U133_Plus_2] Affymetrix Human | ||||||||
Genome U133 Plus 2.0 Array | Genome Microarray 4×44K G4112F | Genome U133 Plus 2.0 Array | Genome U133 Plus 2.0 Array | |||||||||
PMID | 22021740 | 22252466 | 21216829 | 24910450 | ||||||||
GSE No. | GSE21942 | GSE27694 | GSE16461 | GSE52139 |
The ratio listed in the line of "Sample size" is the number of multiple sclerosis (MS) cases compared with that of controls. The genes listed here that are not defined in the main text are major histocompatibility complex, class II, DO beta (HLA-DOB), major histocompatibility complex, class II, DR alha (HLA-DRA), POU class 5 homeobox 1 (POU5F1), uncharacterized LOC100294145 (LOC100294145), tenascin XB (TNXB), psoriasis susceptibility 1 candidate 1 (PSORS1C1), major histocompatibility complex, class II, DM beta (HLA-DMB), transporter 2, ATP-binding cassette, sub-family B (TAP2), allograft inflammatory factor 1 (AIF1), major histocompatibility complex, class I, F (HLA-F), major histocompatibility complex, class II, DQ alpha 1 (HLA-DQA1), respectively.
*Only the most significant probe is listed, even if more than one probe was detected for a gene.
GSE No.: Gene Expression Omnibus number, www.ncbi.nlm.nih.gov/geo/, PMID: PubMed unique identifier.