Skip to main content
. 2014 Nov 12;1(1):ENEURO.0007-14.2014. doi: 10.1523/ENEURO.0007-14.2014

Figure 1.

Figure 1

Barrel patterns and whisker-related activation in the barrel cortex. A, B, VGLUT-2 (green, for TCAs) and Neun (blue, for neurons) double immunostaining reveals that both the TCA terminal segregation and cellular organization into barrels appear normal in CxAC1KO cortex (A). In the ThAC1KO cortex, cellular patterning is absent (note the rather uniform distribution of the Neun-labeled blue cells) and there is some patterning of the TCA terminals (green; B). C, D, VGLUT-2 (blue) and c-fos (pink) immunolabeling in the barrel cortex of a B6 (control, C) and AC1KO (D) mice following row C whisker activation. Note that in the AC1KO cortex, a topographically appropriate zone is activated, although there is no VGLUT-2-related patterning. E, F, VGLUT-2 (blue) and c-fos (pink) immunolabeling in the barrel cortex of exemplary CxAC1KO and ThAC1KO mice following row C whisker activation. Note that the activity pattern in the CxAC1KO cortex is similar to B6 control, while that of the ThAC1KO cortex is similar to the AC1KO cortex. Scale bar, 200 μm.