IL-37a |
Brain, lymph nodes, thymus, bone marrow, lung, testis, placenta, uterus, skin, colon, NK, monocytes, stimulated B cells, keratinocytes |
May be functional |
IL-37b |
Heart, lymph nodes, thymus, bone marrow, lung, testis, placenta, uterus, skin, colon, NK, monocytes, stimulated B cells, keratinocytes |
Biologically functional isoform with the greatest amount of exons. |
IL-37c |
Kidney, lymph nodes, thymus, bone marrow, lung, testis, placenta, uterus, skin, colon, NK, monocytes, stimulated B cells, keratinocytes |
Non-functional, due to abnormal folding |
IL-37d |
Testis and bone marrow |
May be functional |
IL-37e |
Testis and bone marrow |
Non-functional, due to abnormal folding |