Table 4.
Cox regression Analyses of Variables Associated with Survival after Liver-Directed Procedure for Patients with Fibrolamellar Carcinoma (n = 90) from 1986–2008
| Prognostic factor | Univariate
|
Multivariate
|
||||
|---|---|---|---|---|---|---|
| Hazard ratio | 95% CI | p Value | Hazard ratio | 95% CI | p Value | |
| Age >25 y | 1.47 | 0.78–2.77 | 0.237 | 1.61 | 0.84–3.11 | 0.155 |
|
| ||||||
| Female sex | 1.03 | 0.55–1.94 | 0.925 | – | – | – |
|
| ||||||
| Year of diagnosis quartile | ||||||
|
| ||||||
| 1986–2001 | – | Reference | – | – | – | |
|
| ||||||
| 2002–2004 | 1.08 | 0.51–2.31 | 0.835 | – | – | – |
|
| ||||||
| 2006–2006 | 0.71 | 0.21–2.28 | 0.595 | – | – | – |
|
| ||||||
| 2007–2008 | 1.38 | 0.30–6.41 | 0.682 | – | – | – |
|
| ||||||
| Regional disease | 1.41 | 0.75–2.66 | 0.283 | 1.87 | 0.95–3.67 | 0.070 |
|
| ||||||
| Liver-directed procedure | ||||||
|
| ||||||
| Resection or hepatic transplant | – | Reference | – | – | – | |
|
| ||||||
| Ablation only | 2.53 | 0.89–7.20 | 0.118 | 3.01 | 1.02–8.87 | 0.046* |
|
| ||||||
| Surgery, not otherwise specified | 2.16 | 0.66–7.05 | 0.081 | 2.40 | 0.72–8.03 | 0.157 |
*
Significant.