Table 2. Univariate analysis comparing patient’s baseline characteristics, procedure types, intraoperative and perioperative variables and between the 2 groups of patients with cardiac surgery associated AKI (CS-AKI) (group-I) and patients with a normal postoperative kidney function (group II) .
Characteristics |
Group I
CS-AKI (n = 20) |
Group II
Non-AKI (n = 221) |
P value |
Baseline characteristics | |||
%EFa | 51.2±15.4 (15-75) | 49.8±14.8 (10-80) | 0.69 |
Baseline Cra | 1.17±0.27 (0.7-1.7) | 1.03±0.25 (0.5-2) | 0.047 |
Pre-op Hgba | 8.04±1.69 (6.2-12.6) | 7.88±1.27 (5.2-11.5) | 0.68 |
Pre-op Hcta | 24.2±5.23 (18.1-38.4) | 23.3±3.75 (15.3-35.4) | 0.46 |
Pre-transfusion Hgba | 8.69±0.90 (7.5-10.8) | 8.28±0.63 (6.7-9.7) | 0.09 |
Surgery (≤48 h) | 6 (30%) | 38 (17%) | 0.22 |
Blood transfusion (14 d) | 12 (60%) | 47 (21%) | 0.0004 |
Procedure types | |||
CABG | 11 (55%) | 175 (79%) | 0.04 |
Valves | 6 (30%) | 34 (15%) | |
CABG + valves | 3 (15%) | 12 (5%) | |
Intraoperative variables | |||
Operative timea | 273.4±63.19 (186-423) | 255.9± 56.9 (155-518) | 0.24 |
Pump timea | 149.6±48.1 (82-260) | 112.8±36.9 (34-252) | 0.003 |
Clamp timea | 100.9±40.6 (40-218) | 71.3±30.1 (18-188) | 0.005 |
Perioperative MAP | |||
Pre-CPB-MAPa | 77.8±9.39 (60.7-98) | 78.8 (51-105.4) ± 8.51 | 0.66 |
CPB-MAPa | 57.02±4.52 (46-64.6) | 58.03±5.00 (45-81.2) | 0.35 |
∆-MAPa | 20.79± 10.57 (5.3-43) | 19.94±12.36 (47-65) | 0.73 |
ICU-MAPa | 81.61±8.76 (70.3-102.8) | 82.92±10.52 (61.4-118.2) | 0.53 |
Abbreviations: %EF, cardiac ejection fraction; Cr, Creatinine; Pre-op Hgb, pre-operative hemoglobin; Pre-op Hct, pre-operative hematocrit; Surgery (≤48 h), surgery less than 48 hours from heart catheterization; Blood transfusion (14 d), blood transfusion within 14 postoperative days; CABG, coronary artery bypass grafting; Valves, valve surgery; CABG + valves, combined CABG and valve surgery; pump time, duration of CBP; clamp time, aortic cross clamp time; CPB, cardiopulmonary bypass; MAP, mean arterial pressure; ΔMAP, Difference between pre-CPB MAP and CPB MAP; ICU, intensive care unit.
a Figures are presented as mean ± standard deviation (range).