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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Spine J. 2015 Jun 19;15(10):2206–2215. doi: 10.1016/j.spinee.2015.06.049

Table 3.

Adjusted Mean Change from Baseline in Neck Disability Index and Neck Pain Intensity scale at 12 and 26 wks post-baseline. Main effects of primary and booster treatment assignments.

Massage Dose Mean Change (95% CI) Mean Difference (95% CI) P
NECK DISABILITY INDEX

12 WEEK OUTCOME
Primary Treatment
  30min × 2/wk −2.94 (−4.66, −1.23) Ref
  30min × 3/wk −2.72 (−4.44, −0.99) 0.23 (−2.16, 2.61) 0.852
  60min × 1/wk −1.80 (−3.48, −0.11) 1.15 (−1.33, 3.62) 0.365
  60min × 2/wk −2.89 (−4.65, −1.13) 0.05 (−2.41, 2.52) 0.966
  60min × 3/wk −4.25 (−5.92, −2.59) −1.31 (−3.73, 1.11) 0.288
Booster Treatment
  No Further Treatment −1.50 (−2.52, −0.48) Ref
  Booster Treatment −4.36 (−5.47, −3.25) −2.87 (−4.37, −1.36) <0.001
26 WEEK OUTCOME
26 versus 12 week NA −0.59 (−2.37, 1.19) 0.517
Primary Treatment
  30min × 2/wk −2.82 (−4.62, −1.01) Ref
  30min × 3/wk −2.15 (−3.96, −0.35) 0.66 (−1.92, 3.24) 0.616
  60min × 1/wk −2.22 (−4.11, −0.33) 0.60 (−2.04, 3.24) 0.655
  60min × 2/wk −2.86 (−4.70, −1.02) −0.04 (−2.58, 2.49) 0.974
  60min × 3/wk −2.49 (−5.07, 0.09) 0.32 (−2.83, 3.48) 0.841
Booster Treatment
  No Further Treatment −1.79 (−2.90, −0.68) Ref
  Booster Treatment −3.23 (−4.62, −1.84) −1.44 (−3.21, 0.33) 0.110

NECK PAIN INDEX

12 WEEK OUTCOME
Primary Treatment
  30min × 2/wk −2.30 (−3.00, −1.59) Ref
  30min × 3/wk −2.39 (−3.05, −1.72) −0.09 (−1.05, 0.87) 0.854
  60min × 1/wk −1.43 (−2.08, −0.77) 0.87 (−0.09, 1.84) 0.077
  60min × 2/wk −2.19 (−2.76, −1.62) 0.11 (−0.81, 1.03) 0.817
  60min × 3/wk −2.74 (−3.33, −2.15) −0.45 (−1.38, 0.49) 0.349
Booster Treatment
  No Further Treatment −1.90 (−2.31, −1.50) Ref
  Booster Treatment −2.52 (−2.90, −2.13) −0.61 (−1.17, −0.05) 0.032
26 WEEK OUTCOME
26 versus 12 week NA −0.31 (−0.98, 0.36) 0.361
Primary Treatment
  30min × 2/wk −2.31 (−2.95, −1.66) Ref
  30min × 3/wk −2.14 (−2.87, −1.40) 0.17 (−0.79, 1.13) 0.728
  60min × 1/wk −1.50 (−2.30, −0.70) 0.81 (−0.24, 1.85) 0.131
  60min × 2/wk −1.74 (−2.46, −1.02) 0.56 (−0.41, 1.54) 0.257
  60min × 3/wk −1.84 (−2.60, −1.07) 0.47 (−0.54, 1.48) 0.364
Booster Treatment
  No Further Treatment −1.89 (−2.31, −1.48) Ref
  Booster Treatment −1.91 (−2.40, −1.41) −0.01 (−0.66, 0.64) 0.973

Linear regression model including a main effect for each primary treatment assignment and a main effect of booster (i.e. No interaction included between primary and booster treatment assignment) adjusting for baseline NDI and NPI, age, sex, duration of neck pain > 5 years, use of medications for NP, and race (White, Non-Hispanic vs other).