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. 2015 Oct 6;34:114. doi: 10.1186/s13046-015-0231-9

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© Petrizzo et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Analysis of intracellular NP distribution by CLSM. monocytes were loaded with 50 μg/mL PLGA NPs at different time points (a 30 min; b 1 h; c 4 h; d 24 h). Z-series images represent focal planes corresponding to 0.1 μm vertical interval. Internalization areas are indicated by arrows. Original magnification: 630X. Scale bar: 10 μm and 5 μm