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. 2015 Oct 7;10(10):e0139140. doi: 10.1371/journal.pone.0139140

Table 4. Cost, effectiveness and incremental cost-effectiveness ratio of different diffusion levels of PCV–13 (vs. current PPSV–23 strategy).

Diffusion level of PCV13 vs. PPSV–23 Vaccine cost per person Treatment cost per person Total cost per person Effectiveness per person Incremental cost Incremental effectiveness ICER* = (5)/(6)
¥ ¥ ¥ QALY ¥ QALY
(1) (2) (3) = (1)+(2) (4) (5) (6)
0% vs. 100% (Current strategy) 3,860 20,456 24,316 14.31480 - - -
10% vs. 90% 3,987 20,350 24,337 14.31486 21 0.00006 378,000
20% vs. 80% 4,113 20,245 24,358 14.31491 42 0.00011 378,000
30% vs. 70% 4,240 20,140 24,380 14.31497 64 0.00017 378,000
40% vs. 60% 4,366 20,035 24,401 14.31503 85 0.00022 378,000
50% vs. 50% 4,493 19,929 24,422 14.31508 106 0.00028 378,000
60% vs. 40% 4,619 19,824 24,443 14.31514 127 0.00034 378,000
70% vs. 30% 4,746 19,719 24,464 14.31520 149 0.00039 378,000
80% vs. 20% 4,872 19,613 24,486 14.31525 170 0.00045 378,000
90% vs. 10% 4,999 19,508 24,507 14.31531 191 0.00051 378,000

*ICER: incremental cost-effectiveness ratio (¥/QALY gained). All ICERs were rounded to the nearest thousand.