Table 5.
Adjusted hazard ratios with confidence intervals from a Cox model after multiple imputation for all deaths during TB treatment according to age group (<45 years vs. ≥45 years of age)
| <45 years of age | ≥45 years of age | |||
|---|---|---|---|---|
| aHR (95 % CI) | p value | aHR (95 % CI) | p value | |
| Sex female | 0.98 (0.83–1.16) | 0.802 | 1.11 (0.86–1.44) | 0.423 |
| Anatomic site of TB | ||||
| Pulmonary | Reference | Reference | ||
| Extra-pulmonary | 1.16 (0.92–1.47) | 0.213 | 1.20 (0.84–1.69) | 0.313 |
| Both | 1.52 (1.14–2.01) | 0.004 | 1.21 (0.72–2.05) | 0.473 |
| Prior TB | 1.10 (0.92–1.33) | 0.299 | 1.31 (1.01–1.70) | 0.042 |
| HIV infected | 3.16 (2.34–4.27) | <0.001 | 1.18 (0.87–1.59) | 0.282 |
| TB smear result | ||||
| Smear negative | Reference | Reference | ||
| Smear positive | 0.99 (0.81–1.21) | 0.904 | 0.76 (0.56–1.02) | 0.068 |
| No smear performed | 1.21 (0.94–1.56) | 0.142 | 0.87 (0.57–1.31) | 0.501 |
TB tuberculosis, ART antiretroviral treatment, TMP-SMX trimethoprim sulfamethoxazole 160/80 mg chemoprophylaxis, aHR adjusted hazard ratio, 95 % CI 95 % confidence interval