Table 6.

Adjusted hazard ratios with confidence intervals from a Cox model after multiple imputation for all HIV-infected deaths during TB treatment according to age group (<45 years vs. ≥45 years of age)

	<45 years		≥45 years
	aHR (95 % CI)	p value	aHR (95 % CI)	p value
Sex female	1.10 (0.92–1.31)	0.310	1.44 (1.04–2.01)	0.030
Anatomic site of TB
Pulmonary	Reference		Reference
Extra-pulmonary	1.14 (0.89–1.46)	0.273	1.05 (0.66–1.66)	0.838
Both	1.33 (1.00–1.80)	0.052	1.09 (0.59 – 2.01)	0.775
Prior TB	1.13 (0.93–1.37)	0.234	1.39 (0.98–1.97)	0.066
TB smear result
Smear negative	Reference		Reference
Smear positive	1.08 (0.87–1.33)	0.471	0.94 (0.63–1.39)	0.741
No smear performed	1.16 (0.89–1.52)	0.262	0.81 (0.48–1.39)	0.447
CD4 count
<50	Reference		Reference
50–100	0.76 (0.57–1.02)	0.065	0.92 (0.54–1.59)	0.771
100–200	0.51 (0.37–0.70)	<0.001	0.62 (0.38–1.04)	0.068
200–350	0.44 (0.33–0.58)	<0.001	0.40 (0.23–0.70)	0.002
350+	0.23 (0.15–0.37)	<0.001	0.29 (0.13–0.67)	0.005
TMP-SMX chemoprophylaxis	0.83 (0.54–1.27)	0.393	0.96 (0.30–3.04)	0.936
ART during TB treatment	0.67 (0.44–0.83)	<0.001	0.44 (0.27–0.72)	0.001

TB tuberculosis, ART antiretroviral treatment, TMP-SMX trimethoprim sulfamethoxazole 160/80 mg chemoprophylaxis, aHR adjusted hazard ratio, 95 % CI 95 % confidence interval