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Summary of Fbw7α or Fbw7β on PGC-1α degradation rates.
| PGC-1α | +Fbw7α | +Fbw7β | |
|---|---|---|---|
| HeLa | 0.3 +/− 0.02h (38) | 2.9 +/− 0.4h (17) | 0.2 +/− 0.02h (7) |
| Fbw7−/− | 0.8 +/− 0.09h (18) | 2.0 +/− 0.5h (10) | 0.6 +/− 0.04h (9) |
PGC-1α degradation rates in the presence of Fbw7α or Fbw7β were determined as described in Figure 2. Figures indicate mean +/− SEM (number of independent determinations).
