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Subcellular distribution of Fbw7α chimeric proteins.
| % Nuclear | % N≫C | % N~C | % Cyto | |
|---|---|---|---|---|
| Fbw7α | 88 | 12 | 0 | 0 |
| Fbw7α-NLSmut | 0 | 77 | 5 | 18 |
| Fbw7α-NLSdel | 0 | 73 | 4 | 23 |
| Nβ-Fbw7α | 0 | 10 | 6 | 84 |
| Fbw7β | 0 | 3 | 6 | 91 |
Subcellular localization of each Fbw7α chimeric protein was quantified and expressed as % nuclear, % N≫C, % N~C, and % cytoplasmic. Localization of Fbw7α and Fbw7β served as controls.
