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Subcellular distribution of PGC-1α in Fbw7+/+ and Fbw7−/− cells.
| % Nuclear | % N≫C | % N~C | % Cyto | |
|---|---|---|---|---|
| Fbw7+/+ | 0 | 93 | 7 | 0 |
| Fbw7+/+ + MG132 | 0 | 95 | 5 | 0 |
| Fbw7−/− | 0 | 90 | 9 | 1 |
| Fbw7−/− + MG132 | 0 | 96 | 3 | 1 |
Subcellular localization of PGC-1α protein +/− MG132 was quantified and expressed as % nuclear, % N≫C, % N~C, and % cytoplasmic. Fbw7α and Fbw7β served as controls.
