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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Curr Pharmacol Rep. 2015 Jan 30;1(3):179–196. doi: 10.1007/s40495-015-0017-y

Figure 1.

Figure 1

Figure 1

Figure 1

(A) Examples of aliphatic, indole and aromatic glucosinolates found in Brassicaceae vegetables. (B) General model of glucosinolate hydrolysis by myrosinase and specifier proteins indicated as TFP (thiocyanateforming protein) and ESP (epithiospecifier protein). (C) Metabolism of isothiocyanates by the mercapturic acid pathway. Isothiocyanates are conjugated to glutathione by glutathione S-transferases (GSTs) and successively cleaved by γ-glutamyltranspeptidase (γ-GT), cysteinylglycinase (CGase), and N-acetyltransferase (AT) to create N-acetylcysteine conjugates (mercapturic acids).